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ACE-inhibitors and angioedema

  • Although uncommon or rare, angioedema (swelling of the face, lips, tongue, or throat) can occur at any time while taking an ACE inhibitor, even if you have been taking it for a long period without problems
  • Seek urgent medical attention if you develop swelling of the face, lips, tongue, or throat, or experience difficulty breathing or swallowing whilst taking ACE inhibitors
  • Do not take further doses of your ACE inhibitor if angioedema is suspected and inform a healthcare professional immediately
  • Inform healthcare professionals if you have ever experienced angioedema, including while taking an ACE inhibitor.  Please be aware that angioedema can occur for other reasons, and a healthcare professional may still recommend an ACE inhibitor for you in these instances

Page published: 23 June 2026
Last updated: 23 June 2026